Endocrine Abstracts

Aim: Most research teams analyze the evolution of patients with Hashimoto thyroiditis (HT) on syndromic basis (e.g., the thyroid function), not on pathogenic basis (the autoantibodies). Thus, most researchers refer to thyroid hormone evolution. In this study we re-analyzed (first in 2018) how evolve the antithyroid autoantibodies. Therefore, we analyzed the antithyroperoxydase antibodies (ATPO) evolutive patterns in patients with HT.Method: 1. ATPO level...

Aim: Has testosterone undecanoat 1000 mg intramuscular injection (NebidoR; Bayer), 1 at 3month, negative effect on prostate? For this purpose, we appreciate the prostatic volume (see Pisoschi, this congress) and PSA (this study) in hypogonadic patients after testosterone injection up to 11 years.Material and method: A. PSA (ng/ml) was done in Bucharest accredited laboratories.B. Patients: PSA analysis was done before tre...

Aim: Re-Analysing (study starting in 2007) the effect of injectable testosterone undecanoat depot (TUD) in hypogonadic patients.Material-method: A. Patients: at onset 278 men with hypogonadism (median: 61 y).B. Distribution: by decade (starting with 20y); no =6, 17, 25, 70, 86, 55, 18, 1.C. TUD (NebidoR-Bayer) 1000 mg injected one/3 months i.m.D. Prostate volume (PV) apprecia...

AimRe-Analysing (starting 2007) the effect of injectable testosterone undecanoat depot (TUD) in hypogonadic patients.Material-methodA. Patients: at onset 333 men with hypogonadism (median: 62 y).B. Distribution: by decade (starting with 20y->90y); no = 6, 18, 35, 80, 104, 67, 21, 2.C. TUD (Neb...

AimWe appreciate the effect of testosterone undecanoat 1000 mg intramuscular injection (NebidoR; Bayer) on both prostatic volume (see Peretianu, this congress) and PSA (this study) in hypogonadic patients after up to 13 years.Material and methodA. PSA (ng/ml) was done in Bucharest accredited laboratories, appreciated at 1 year. B. Prostatic volume (PV): ultrasound,...

AbstractAim and objectives: To investigate the prevalence of relationships between kin/relatives with a known thyroid immune disorder related to Hashimoto thyroiditis.Material and method: 1. Thyroid disease diagnosis: a. ATPO > 34 u/ml = Hashimoto thyroiditis (HT); b. ATPO = normal but with high antithyroglobuline (ATG) = thyroiditis with only hyper-ATG (T-ATG); c. hypothyroidism without high ATPO/ATG = idiopat...

Aim: Most research teams analyze the evolution of patients with Hashimoto thyroiditis (HT) on syndromal basis, not on pathogenetic basis. Thus, most researchers refer to thyroid function evolution. In this study we tried to show how evolve the antithyroid antibodies. Therefore, we analyzed ATPO evolutive patterns.Method: (1) ATPO levels were analyzed in several accreditated Bucharest laboratories. (2) Only patients with minimum 3 investigations were cons...

Aim: The biological diagnostic of Hashimoto thyroiditis (HT) is based on higher than normal levels of antithyroperoxydase antibodies (ATPO). Our goal was to establish the cut-off limit of normality (the upper limit) for ATPO in our thyroid normal patients. This limit, and not that of the laboratory, should be used as diagnosis of Hashimoto thyroiditis.Material and method: 1. ATPO was investigated in patients with normal level of thyroid hormones (euthyro...

Background: Hashimoto thyroiditis (HT) is defined as thyroid chronic inflammation due to high level antithyroperoxydase antoantibodies (ATPO) and/or antithyroglobuline autoantibodies (ATG) and their destructive process on thyroid cell. The diagnostic uses specific and very characteristic ultrasound features. What diagnosis has to have those patients with ultrasound features of HT, who are hypothyroid, but with normal levels of ATPOs and normal levels of ATGs ?<p c...

Introduction: Trabecular bone score (TBS) was introduced in FRAX, to evaluate more precisely the risk for fracture. However, FRAX is a method for editing a risk, not for making a diagnosis. WHO established conventionally, based on the level of standard deviation (SD), named T score, for Bone Mineral Density (BMD) that <−2,5 SD is compatible with the diagnosis of osteoporosis.Aim: Our aim was to analyze if it is possible to used T score (SD) for...